According to Press TV, Zarif left the Iranian capital, Tehran, on Thursday, and is being accompanied by his Deputy for Arab-African Affairs Hossein Amir-Abdollahian.
The ISSG meeting, aimed at finding a solution to the nearly five years of conflict in Syria, is scheduled to be held in Munich later on Thursday.
German Foreign Minister Frank Walter Steinmeier announced on Sunday that Zarif and Saudi Foreign Minister Adel al-Jubeir, who support opposing sides in the conflict in Syria, would take part in the ISSG session.
According to a statement by the German Foreign Ministry, apart from those of Iran and Saudi Arabia, diplomatic delegations from China, Egypt, France, Germany, Iraq, Italy, Jordan, Lebanon, Oman, Qatar, Russia, Turkey, the United Arab Emirates, the UK, the US as well as the Arab League, the European Union and the United Nations will also attend the meeting.
The latest round of the talks between the Syrian government and the Saudi-backed Syrian opposition in the Swiss city of Geneva was adjourned last week. February 25 has been set as the date for the resumption of the talks.